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Hofmann's isolation of psilocybin

How to Change Your Mind

Albert Hofmann’s isolation of Psilocybin is identified in the book as a core-evidence subject in the history of the compound. The reference links the isolation to passages on Psilocybin’s discovery and synthetic form, but the available text does not supply a narrative account of how the work was performed or when it took place.

Identification in the Book

The book’s index marks Hofmann’s isolation of Psilocybin as core evidence and directs readers to a discussion on page 113. It separately indexes the compound’s discovery at page 83. These references place the isolation within the book’s account of Psilocybin’s scientific history, while leaving the relationship between discovery and isolation unexplained in the evidence available here.

Isolation and Synthetic Form

The index also identifies a synthetic version of Psilocybin as core evidence, with references to pages 83–84 and 113. Its proximity to the entry on Hofmann’s isolation connects the topics in the book’s reference structure, but does not establish the method, sequence, or circumstances of the synthesis. No laboratory procedure, date, or account of Hofmann’s actions is preserved in the supplied passages.

Scientific Context and Evidentiary Limits

Elsewhere, the index classifies Psilocybin as a tryptamine and points to a discussion on page 291. It also has an entry for the compound’s effects on brain activity, although the supplied fragment does not include the associated page reference or describe those effects. Together, these entries show that the book treats Psilocybin across historical, chemical, and neuroscientific contexts. They do not, on their own, provide enough detail to reconstruct Hofmann’s isolation or assess its experimental significance.