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Leo Zeff

How to Change Your Mind

Leo Zeff was an Oakland Jungian therapist who became one of the best-known practitioners of underground psychedelic therapy. His importance lay not only in treating patients with psychedelics, but in helping shape how guides prepared for, conducted, and took responsibility for those sessions. After psychedelic drugs were placed in Schedule I in 1970, Zeff chose to continue his work outside the law; the practices he developed and passed on helped preserve a body of therapeutic knowledge that later reached both underground guides and university research.

Identity and Introduction

Zeff was forty-nine and practicing as a Jungian therapist in Oakland when he took LSD for the first time in 1961. His guide had asked him to bring an object of personal significance, and Zeff chose his Torah. Once the drug’s effects began, the guide laid the Torah across his chest. Zeff described the experience as an encounter with God and a feeling of oneness. The episode gave him a personal point of entry into psychedelic treatment, but the book presents its consequence as professional as well as spiritual: he soon began incorporating several kinds of psychedelics into his work with patients.

The account of Zeff’s life survives in part through a deliberate disguise. His close friend Myron Stolaroff published a series of interviews with him in 1997 under the title The Secret Chief, presenting him as a therapist called Jacob. In 2004, Zeff’s family gave Stolaroff permission to disclose his identity and republish the book as The Secret Chief Revealed. Zeff’s pseudonym therefore became attached to an account that could circulate when the work itself had to remain hidden.

The book resists casting him as a theatrical outlaw or self-appointed guru. In the photograph included in the 2004 edition, Zeff wears aviator glasses and a sweater vest over his shirtsleeves; the narrator finds that he looks more like a favorite uncle than a renegade or mystic. The contrast matters: the underground practice described here depended on a therapist who could appear ordinary while carrying out work that placed him beyond conventional professional and legal boundaries.

From Clinical Practice to Underground Work

Zeff found that psychedelics could help patients move past their defenses, bring less accessible psychological material into view, and arrive at spiritual insights, sometimes in a single session. He regarded the results as compelling enough to keep treating patients after the federal government placed psychedelics in Schedule I in 1970, prohibiting their use for any purpose. His decision marked a change in the conditions of his work, not an end to it: the practice continued, but underground.

That choice brought lasting personal strain. In his account to Stolaroff, Zeff described repeatedly reconsidering the risks and asking himself why he should continue exposing himself to them. He returned to the effects he saw in his patients as his reason for staying with the work. The testimony gives his persistence a practical ground: he weighed the danger against the changes he believed treatment was producing, rather than presenting continued practice as a simple refusal to recognize the consequences.

Zeff also became one of the best-known underground therapists. He claimed to have processed three thousand patients and trained 150 guides over the course of his career. Those figures indicate the scale of influence he attributed to his work, while the book places his reputation within a wider lineage: many of the underground guides interviewed by the author could trace their professional inheritance back to Zeff, alongside figures such as Timothy Leary, Stanislav Grof, and Al M Hubbard. A guide in her eighties who led the author’s later ayahuasca circle had trained under Zeff; she in turn had trained Mary, who guided the author’s psilocybin session. His influence thus appears not only in formal accounts, but in person-to-person transmission across generations of practice.

Protocols, Trust, and the Guide’s Role

Zeff helped codify the agreements that underground guides typically made with clients. They addressed strict confidentiality, a prohibition on sexual contact, and the client’s absolute obedience to the therapist’s instructions during the session. In a setting where participants could be unusually open to suggestion, such agreements gave the encounter a structure of responsibilities and limits. They also made explicit that the work was not simply the private administration of a drug: it involved a guide, a client, and rules governing their relationship.

He developed ceremonial elements as well. One was having participants take the medicine from a cup, which he considered an important symbol of transformation. In Zeff’s approach, ritual was not decorative. The cup and the agreements helped give form to an experience whose psychological intensity could otherwise outstrip the ordinary conventions of therapy.

His view of the guide’s conduct departed from the ideal of detached analysis. Zeff believed a guide should have personal experience with any medicine he or she administered. He also argued that guides should not direct or manipulate the journey, but allow it to find its own course and destination. At the same time, noninterference did not require emotional distance: he considered it appropriate for guides to show their personalities and feelings and to offer comforting touch or a hug when a client was undergoing a difficult experience. The combination is distinctive. The guide should not impose an interpretation on the journey, but should remain personally present and responsive to the person moving through it.

Legacy and Influence

Stolaroff’s introduction to The Secret Chief Revealed cast Zeff as part of the underground lineage that contributed to the revival of legitimate psychedelic research beginning in the late 1990s. In that account, the new university research drew not only on the first wave of studies in the 1950s and 1960s, but also on anecdotal knowledge accumulated by underground therapists. The influence was not merely retrospective: some underground practitioners were recruited to help train guides for university trials, and when the Johns Hopkins team wanted to investigate music in guided psilocybin sessions, it consulted underground guides about their musical practices.

Zeff’s legacy also includes his early use of MDMA in therapy. The compound was popularized by his friend Alexander “Sasha” Shulgin and Shulgin’s wife, therapist Ann Shulgin; Zeff was among the first therapists to use it, beginning in the 1970s. In the later account of underground practice, guides describe MDMA as a way to lower psychological defenses and establish trust before a psychedelic journey. It is not presented as a classical psychedelic: it acts on different brain receptors, produces few strong visual effects, and, as an amphetamine, raises cardiovascular considerations distinct from those of classical psychedelics.

Zeff’s significance rests in this joining of clinical practice, personal experience, ritual, and inherited technique. The author’s account traces a line from Zeff’s work to protocols used by later underground guides and to knowledge entering university trials, even as researchers could be reluctant to acknowledge that traffic between the two worlds. His career shows how a practice excluded from legal medicine could nonetheless preserve and transmit methods that later researchers found useful.

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