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The narrator's psilocybin journey

How to Change Your Mind

The narrator’s second psychedelic journey, undertaken with guide Mary Cosimano, becomes a decisive encounter with the possibility of existing without the familiar ego at the center of experience. A carefully prepared session leads through disorienting images, the dissolution of the narrator’s usual sense of self, and a confrontation with the deaths of loved ones. Its meaning does not arrive fully formed: the next day’s integration turns a jumble of impressions into an account of how the experience might change the narrator’s relation to fear, grief, and other people.

Preparation and setting

The journey begins in a suburban loft around an altar that Cosimano has arranged and prayed over. Her invocation calls on the cardinal directions, the elements, and the animal, plant, and mineral realms. The setting gathers personal objects and ceremonial symbols: an embroidered cloth from Peru, a heart-shaped amethyst, a candle, small cups of water, dark chocolate, and two objects the narrator has brought—a bronze Buddha and a psilocybin coin given by Roland Griffiths. An antique plate holds a notably large mushroom, which the narrator is expected to eat whole.

Rather than make a tea, the narrator follows Cosimano’s suggestion to examine and eat the mushroom bite by bite. Chocolate helps make this possible. The first portion amounts to two grams; Cosimano plans another two grams later, for a total of four. The text places that amount alongside the doses used in the NYU and Johns Hopkins trials, and estimates it as roughly equivalent to three hundred micrograms of LSD, twice the amount the narrator had taken with Fritz.

After about twenty minutes of quiet conversation, Cosimano notices the narrator’s flushed face and suggests lying down with eyeshades. The narrator chooses a Mindfold mask designed by psychedelic artist Alex Grey. Cosimano plays music, and the first track accompanies an imagined digital city. The episode makes the session’s setting more than a backdrop: the music and the mask’s black foam become part of the visual world, while a later attempt to test a visual illusion is complicated by a video image already cued on the narrator’s laptop. In the integration conversation, Cosimano proposes that the image may have helped shape the computer-like landscape, an example of how expectations and surroundings can influence the experience.

Dissolving self and confronting death

After the dose increases, the narrator returns to the digital landscape but no longer experiences it from the same stable perspective. The familiar self appears to break apart into small scraps of paper scattered across the scene. Instead of trying to gather them, the awareness witnessing their dispersal feels unconcerned. The narrator then imagines the self spread across the landscape like paint: what had been experienced as an inward subject is now something observed as part of the world.

This shift is not described as simple unconsciousness or as an uncomplicated mystical certainty. The narrator distinguishes the ordinary, defended ego from a more impersonal awareness that observes its dissolution. The latter feels calm and content, and the narrator interprets the experience as evidence that the loss of the familiar self need not mean total annihilation. The account considers whether this awareness might resemble Aldous Huxley’s idea of Mind at Large, but does not conclude that consciousness exists outside the brain. A brain-based explanation remains plausible; what matters to the narrator is the experienced discovery of another possible vantage point.

After taking the remaining mushroom, the narrator enters a landscape of bones and images of deceased relatives, friends, teachers, and the narrator’s father-in-law. The experience brings forward a recognition that these losses had not been fully mourned. When an aunt’s face seems to become Judith’s, the association joins grief to the fear of Judith’s breast cancer: the aunt had died of breast cancer, while Judith had survived it. The narrator’s defenses give way, and tears follow. The episode makes mourning, rather than abstract speculation, one of the journey’s central actions.

Music, death, and reconciliation

For the final passage, the narrator asks Cosimano to replace the earlier music with Bach’s second unaccompanied cello suite, performed by Yo-Yo Ma. The narrator experiences the music not at a distance but as a sequence of changing perspectives within the sound and the cello itself. At roughly four hours into the journey and after four grams of mushroom, the boundary between observer and object becomes difficult to maintain. The cello’s strings, the sound moving outward, and the instrument’s resonant interior become successive positions from which the music is experienced.

The narrator describes this loss of separation as a temporary reconciliation with death. The music accompanies thoughts of the people already lost, including Bob, Ruthellen, and Roy, Judith’s father, and others, as well as deaths still to come and the narrator’s own mortality. The episode does not establish that the fear or reality of death has permanently disappeared. Instead, the journey makes surrendering the usual self feel like a practice for accepting loss, and the experience of the music offers a brief sense of being beyond suffering and regret.

Integration and lasting significance

The next day, the narrator returns to Cosimano’s room for a couple of hours of integration. Telling the story and discussing it helps organize what had initially been disconnected images and fragments. The narrator also recognizes that shaping an ineffable experience into a coherent narrative changes it, while judging that without language its contents would remain unavailable for reflection.

One immediate result is a reassessment of a longstanding fear: that a psychedelic experience might awaken psychological forces the narrator could not control. Nothing terrible happened during this session, and the narrator wonders whether this indicates greater psychological resilience than expected. Cosimano cautions against treating one journey as a guarantee, observing that a different self is brought to each journey and that frightening material could emerge another time. The experience offers evidence about this particular session, not proof that future sessions will be harmless.

The more valuable discovery, as the narrator understands it after the discussion, is that the ego can dissolve without the narrator struggling to restore it, leaving a less neurotic and more generous perspective. Cosimano suggests that meditation may help cultivate a different way of responding, although the narrator’s familiar ego returns within a day. The journey’s significance therefore rests not on permanent transformation but on giving the narrator a temporary example of another mode of attention.

The narrator connects that possibility to the volunteers encountered in research on cancer-related anxiety and smoking. A temporary release from reflexive self-protection may help people relate differently to fear and addiction, while a felt sense of interconnectedness can extend attention beyond the individual self. The psilocybin experience itself lasts only hours; its possible consequence is the chance to recognize and practice a less defended way of being. The account thus treats the journey as both an event in the mind and material for later interpretation, with integration bridging the two.