The Nature of Friendship and Sacrifice
Of Mice and MenTraces the theme that true friendship involves sacrifice, as demonstrated by George's decision to kill Lennie out of love and mercy.
increasing
Bearing strength in each event
decreasing
Friendship as Responsibility

The Burden of Friendship
George's Role
George is responsible for Lennie. He feeds him, protects him, and guides him. The friendship is a burden, but George accepts it. He does not leave Lennie, even when he could.
The Companionship
Despite the burden, the friendship is also a source of companionship. George and Lennie have each other, which is more than the other men have. The friendship is a rare gift.
The Cost of Friendship
Friendship costs George. He loses his freedom, his money, and his peace of mind. But he gains a purpose. The novel explores the cost of friendship and the value of it.
Friendship as Sacrifice

The Ultimate Sacrifice
The Decision to Kill
George's decision to kill Lennie is the ultimate sacrifice. He gives up his own happiness to save Lennie from a worse fate. The sacrifice is an act of love.
The Loss of the Friend
After the killing, George is alone. He has sacrificed his friend for the sake of mercy. The friendship is lost, but the act of sacrifice defines it.
The Meaning of Friendship
The novel suggests that true friendship means being willing to bear the unbearable for the other. George's sacrifice is a model of profound friendship. The theme is that friendship is not just about companionship; it is about sacrifice.
The beginning of the novel
The end of the novel